张世华，博士，教授，硕士博士生导师，主要研究方向为机器学习/人工智能、生物信息学、AI与医药，健康大数据挖掘。2006年和2010年先后毕业于华中科技大学和哈尔滨医科大学，获硕士博士学位，茶树生物学与资源利用国家重点实验室博士后，2016-2017美国佐治亚大学访问学者，主要讲授《程序设计语言》和《数据结构》等课程。

主持科研项目：

国家自然科学基金（62172312,31301248）

中国博士后基金面上项目（2013M531498）

中央高校专项资金项目（CZZ24010）

国家重点实验室开放课题(SKLTOF20160113）

学术任职：

外国优秀青年学者研究基金评审专家

国家自然科学基金评审专家

中国计算机学会生物信息学专业委员会委员

中国人工智能学会生物信息学与人工生命专业委员会委员

中国生物信息学学会多组学与整合生物学专委会委员

湖北省生物信息学会理事

湖北省第十一届博士服务团入选者

BIIP2021/ICIC2022等会议的program member

代表性论文：

1. Bo Li, Chen Peng, Zeran You, Xiaolong Zhang, Shihua Zhang^*, Single-cell RNA-sequencing data clustering using variational graph attention auto-encoder with self-supervised learning, Briefings in Bioinformatics, 2023, 24(6), 1-15

2. Shihua Zhang, Xiaolong He, Rui Zhang, and Wensheng Deng, LncR2metasta: a manual curated database for experimentally supported lncRNAs during various cancer metastatic events, Briefings in Bioinformatics, 2021, 22(3), 1-6

3. Bo Li, Yihui Tian, Yang Tian, Shihua Zhang*, and Xiaolong Zhang*, Predicting Cancer Lymph-node Metastasis from LncRNA Expression Profiles using Local Linear Reconstruction Guided Distance Metric Learning, IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2022, DOI: 10.1109/TCBB.2022.3149791

4. Shihua Zhang, Hongdong Xuan, Liang Zhang, Sicong Fu, Yijun Wang, Hua Yang, Yuling Tai, Youhong Song, Jinsong Zhang, Chi-Tang Ho, Shaowen Li and Xiaochun Wan, TBC2health: a database of experimentally validated health-beneficial effects of tea bioactive compounds, Briefings in Bioinformatics 2017, 18(5), 830-36

5. Shihua Zhang, Ying Chen, Xiaolong He, Jinke Du, Rui Zhang, Yong Ma, Xiaoyi Hu, Zhaoliang Zhang, Qi Chen, and Xiaochun Wan*, Identification of MYB Transcription Factors Regulating Theanine Biosynthesis in Tea Plant Using Omics-Based Gene Coexpression Analysis, Journal of Agricultural and Food Chemistry 2020, 68 (3), 918-926

6. Rui Zhang, Yong Ma, Xiaoyi Hu, Ying Chen, Xiaolong He, Ping Wang, Qi Chen, Chi-Tang Ho, Xiaochun Wan, Youhua Zhang and Shihua Zhang*, TeaCoN: a database of gene co-expression network for tea plant (Camellia sinensis), BMC Genomics 2020, 21:461

7. De’en Yu, Cheng Zhang, Yeman Zhou, Heng Yang, Chen Peng, Feng Zhang, Xinghua Liao, Yuan Zhu, Wensheng Deng, Bo Li, and Shihua Zhang*, ncR2Met (lncR2metasta v2.0): An updated database for experimentally supported ncRNAs during cancer metastatic events, Genomics 2023, 115(2): 110569

8. Jing Lu, Dongqiao Zheng, Mengshuang Li, Maoyin Fu, Xianchen Zhang, Xiaochun Wan, Shihua Zhang*, and Qi Chen*, A Hierarchical Model of ABA-Mediated Signal Transduction in Tea Plant Revealed by Systematic Genome Mining Analysis and Interaction Validation, Tree physiology 2023

9. Tong Zhang, Yixuan Lin, Weimin He, FengXin Yuan, Yu Zeng, and Shihua Zhang*, GCN-GENE: A novel method for prediction of coronary heart disease-related genes, Computers in Biology and Medicine, 2022, 105918

教材撰写：

《生物信息学》、科学出版社、“十四五”普通高等教育本科规划教材、编委

欢迎加入本课题组

本课题组希望招收深度学习算法，AI与生物医药交叉研究方向的硕士研究生。

联系方式：

E-mail：zhangshihua-at-scuec.edu.cn

Lab URL: http://www.wchoda.com/zhanglab.html