出生年月:1972-03
民族:汉
职称:副教授
学科专业:药物化学
研究方向:药物合成/药物分子设计
电子邮箱:kangdai688@163.com
学习与工作简历(按照时间顺序)
1989/09-1993/06,华中理工大学,化学系,应用化学专业,理学士
1993/07-1994/08,中国科学院武汉植物研究所,助研
1994/09-1997/06,同济医科大学,药学院,药物化学专业,医学硕士
1997/07-1999/08,同济医科大学,药学院药物化学专业,助教
1999/09-2002/06,华中科技大学,同济医学院,环境医学专业,医学博士
2002/10-2005/01,美国科罗拉多大学,卫生与健康研究中心,博士后
2005/05-至今,威尼斯wns8885556,药学院,副教授
承担主要项目(已结题)
1.国家自然科学基金面上项目,30471432,离子鳌合MIP高效特异性处理水中重金属污染物,21万,2005.1~2007.12,已结题,主持。
2.国家自然科学基金青年科学基金项目,20307004,分子识别原位捕获检测源水中痕量POPs,23万,2004.1~2006.12,已结题,主持。
3.湖北省自然科学基金面上项目,2014CFB92,金葡菌细菌耐药外排泵抑制剂虚拟筛选和活性检测,3万,2015.1~2016.12,已结题,主持。
4. 国家自然科学基金委员会, 面上项目, 21978329, 微重力下梯度型快速环境响应凝胶的构建、结构模拟及释药示踪, 2020-01-01 至 2023-12-31, 63万元, 资助期满, 参与
5.国家自然科学基金青年科学基金项目,21102185,基于碱性氨基酸骨架的氨肽酶N抑制剂的设计、合成及活性研究,25万,2012.01-2014.12,已结题,参与。
6.国家自然科学基金青年科学基金项目,30200061,基于分子印迹的蓝藻毒素快速传感系统,20万,2003.1~2005.12 ,已结题,参与。
代表性研究成果
专利
1.戴康,刘向明,陈素,温秋玲;一种剑叶龙血素B的合成方法,2013.8,中国专利,授权号:ZL201110122301.8。
2.戴康,袁琳,温超;一种具有抗菌增效作用的化合物及其制备方法和应用,2014.10,中国专利,授权号:ZL201310375755.5。
3.戴康,梅之南,方华,万青;一种具有镇痛作用的化合物及其制备方法,中国专利,2016.5,授权号:ZL201410761064.3。
4.高新蕾, 戴康.一种根据化学结构预测润滑基础油抗磨损性能的方法. 中国发明专利,专利申请日期:2013.5.30,申请号: 201310209235.7.专利公布日期:2013.9.11,专利公布号:CN103294863。
学术论文
1. Kang Dai, Xue-Jia Yi, Xian-Ju Huang*, Azhar Muhammad, Mei Li, Jun Li, Guang-Zhong Yang, and Yue Gao, Hepatoprotective activity of iridoids, seco-iridoids and analog glycosides from Gentianaceae on HepG2 cells via CYP3A4 induction and mitochondrial pathway, Food Funct., 2018, 9, 2673-2683.
2.Xinlei Gao, Zhan Wang, Hong Zhang, Kang Dai, A Three-Dimensional Quantitative Structure Tribo-Ability Relationship Model, J. Tribology, 2015, 137:021802
3.Kang Dai, Xinlei Gao, Estimating antiwear properties of lubricant additives using a quantitative structure tribo-ability relationship model with back propagation neural network, Wear, 2013, 306:242-247
4.K Dai; AG Vlessidis, NP Evmiridis*, Dialysis membrane sampler for on-line flow injection analysis/chemiluminescence-detection of peroxynitrite in biological samples, Talanta, 2003, 59: 55-65.
5.Kang Dai. A Novel Two-Dimension Graphical Representation of DNA Sequences and its Numerical Characterization. IEEE 1st International Conference on Bioinformatics and Biomedical Engineering, 2007, 276-279.
6.Kang Dai. CYP3As Phylogeny Based on 2D-Graphical Representation of Completed Genomic DNA Sequences. IEEE 1st International Conference on Bioinformatics and Biomedical Engineering, 2007, 219-221.
7.K Dai; NP Evmiridis, A Vlessidis. Chemiluminescence detection of peroxynitrite with flow injection. Proceedings SPIE, 4414(2001): 104-7.
8. Meng Liu; Dan Zhao; Hui Lv; Yunjing Liang; Yannan Yang; Zongguo Hong; Jingxue Liu; Kang Dai; Xincai Xiao ; Controllable fabrication and oil–water separation properties of polyethylene terephthaloyl-ethylenediamine-IPN-poly (N-isopropylacrylamide)microcapsules, Polymers, 2023, 15(1): 53
9. Hongfei Tan; Dan Zhao; Mingxing Liu; Zongguo Hong; Jingxue Liu; Kang Dai; Xincai Xiao ; Docking design of the different microcapsules in aqueous solution and its quantitative on-off study, Polymers, 2023, 15(5): 1131
10.Y Lin, Y Shi, M Jiang, Y Jin, Y Peng, B Lu, K Dai. Removal of phenolic estrogen pollutants from different sources of water using molecularly imprinted polymeric microspheres. Environ. Pollut. 2008,153:483-491
11.Y Jin, M Jiang, Y Shi, Y Lin, Y Peng, K Dai, B Lu. Narrowly dispersed molecularly imprinted microspheres prepared by a modified precipitation polymerization method. Anal Chim Acta,2008, 612: 105-113
12.Hu ML, Jiang M, Wang P, Mei SR, Lin YF, Hu XZ, Shi Y, Lu B, Dai K. Selective solid-phase extraction of tebuconazole in biological and environmental samples using molecularly imprinted polymers. Anal Bioanal Chem. 2007;387(3):1007-16
13.Shi Y, Zhang JH, Shi D, Jiang M, Zhu YX, Mei SR, Zhou YK, Dai K, Lu B. Selective solid-phase extraction of cholesterol using molecularly imprinted polymers and its application in different biological samples. J Pharm Biomed Anal. 2006, 42(5):549-55.
14.Ming Jiang, Jiang-Hua Zhang, Su-Rong Mei, Yun Shi, Li-Jun Zou, Ye-Xiang Zhu, Kang Dai, Bin Lu. Direct enrichment and high performance liquid chromatography analysis of ultra-trace Bisphenol A in water samples with narrowly dispersible Bisphenol A imprinted polymeric microspheres column. Journal of Chromatography A, 2006, 1110:27-34
15.Zhang, Jiang-hua, Ming Jiang . Lijun Zou . Dan Shi . Su-rong Mei . Ye-xiang Zhu . Yun Shi. Dai Kang. Lu Bin. Selective Solid-Phase Extraction of Bisphenol A Using Molecularly Imprinted Polymers and Its Application in Biological and Environmental Samples. Anal Bioanal Chem, 2006, 385(4):780-6.