出生年月：1989-04
民族：汉
职称：讲师
学科专业：药物化学
研究方向：天然药物化学/真菌化学
电子邮箱：2021068@mail.scuec.edu.cn
一、教育和工作经历
2023.04-至今：威尼斯wns8885556，药学院，讲师
2021.07-2024.07：威尼斯wns8885556，药学院，预备师资
2018.09-2021.07：中国科学院昆明植物研究所，理学博士
2015.09-2018.07：中国科学院昆明植物研究所，理学硕士
2011.09-2015.07：云南农业大学，农学学士
二、研究方向：
1.药用植物药效物质基础及生物功能研究
2.真菌天然产物的结构及生物功能研究
三、主持的科研项目：
(1) 国家自然科学基金青年基金项目, 82204239，2023-01至2025-12，主持
(2) 湖北省自然科学基金青年基金, 2022CFB920，2022-12至2024-06，主持
(3) 中央高校基本科研业务费专项资金自科青年项目, CZQ23047, 2023-04至2026-04，主持
四、代表性研究成果
(1) Shi Baobao, Lu Jingsong, Wu Jing, Bao Meifen, Cai, Xianghai , Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia. Organic Chemistry Frontiers, 2021, 8(11): 2601-2607.
(2) Shi Baobao, Kongkiatpaiboon Sumet, Chen Gao, Schinnerl Johann, Cai* Xianghai, Nematocidal alkaloids from the roots of Stemona mairei (H.Lév.)K.Krause and identification of their pharmacophoric moiety. Bioorganic Chemistry, 2023, 130: 106239.
(3) Ai Honglian1, Shi Baobao1, Li Wei1, He Juan, Li Zhenghui, Feng Tao*, Liu Jikai*, Bipolarithizole A, an antifungal phenylthiazole-Sativene merosesquiterpenoid from potato endophytic fungus Bipolaris eleusines. Organic Chemistry Frontiers, 2022, 9(7): 1814-1819.
(4) Shi BaoBao1, Tian Chun1, Lv Xiao, Schinnerl Johann, Ye Ke, Guo Hui, Xu Fan, He Yu, Ai, HongLian* ; Liu JiKai*, Boerelasins A-D, Four Unprecedented Cytochalasins from the Endophytic Fungus Boeremia Exigua. Journal of Organic Chemistry, 2023, 88: 13926-13933
(5) Shi Baobao1, Ai Honglian1, Duan Kaiting, Feng Tao*, Liu Jikai*, Ophiorrhines F and G, key biogenetic intermediates of ophiorrhine Alkaloids from Ophiorrhiza japonica and their immunosuppressant activities. Journal of Natural Products, 2022, 85(2): 453-457.
(6) Shi BaoBao1, Xu Fan1, Zhang GuangRu, He Yu, Liu Qing, Feng MengLin, Li ZhengHui*, Liu JiKai*. Glucoconjugated monoterpene indole alkaloids with xanthine oxidase inhibitory activity from Ophiorrhiza japonica. Phytochemistry, 2024, 224, 114169.
(7) Fan YinZhong, Tian Chun, Tong ShunYao, Liu Qing, Xu Fan, Shi BaoBao*, Ai HongLian*, Liu JiKai*, Chromones from the endophytic fungus Bipolaris eleusines. Phytochemistry, 2024, 221: 114046.
(8) Fan YinZhong, Shi BaoBao*. Endophytic fungi from the four staple crops and their secondary metabolites. International Journal of Molecular Sciences, 2024, 25(11): 6057
(9) Ai Honglian1, Lv Xiao1, Ye Ke, Wang Mengxi, Huang Rong, Shi, Baobao*, Li, Zhenghui*. Four new highly oxygenated eremophilane sesquiterpenes from an endophytic fungus Boeremia exigua Isolated from Fritillaria hupehensis. Journal of Fungi, 2022, 8:492.
(10) Shi Baobao, Chen, Jing, Bao, Meifen, Zeng Ying*, Cai, Xianghai*. Alkaloids isolated from Tabernaemontana bufalina display xanthine oxidase inhibitory activity. Phytochemistry, 2019, 166: 112060.
(11) Zhang Xian, Fan Yinzhong, Ye Ke, Pan Xiaoyan, Ma Xujun, Ai Honglian*, Shi Baobao*, Liu Jikai*. Six unprecedented cytochalasin derivatives from the potato endophytic fungus Xylaria curta E10 and their cytotoxicity. Pharmaceuticals, 2023, 16: 193
(12) Shi Baobao1, Zhang Guangru1, Li Zhenghui *, Liu Jikai*. Three new oxygenated yohimbane-type alkaloids from Ophiorrhiza japonica. Fitoterapia, 2023, 166: 105442.
(13) Shi Baobao, Wang Fang, Chen Gao, Schinnerl Johann*, Zeng Ying*, Cai*, Xianghai. Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities. Tetrahedron, 2021, 79: 131783.
(14) Tian Chun, Xu Fan, He Yu, Ai Hong-Lian, Shi BaoBao*, Liu JiKai,* Isolation, absolute configuration and immunosuppressant activities of pyrrole and furanone derivatives from the edible mushroom Grifola frondose. Phytochemistry Letters, 2024, 61, 242-243
(15) Xu Fan1, Pan Xiaoyan1, Cai Baixiang, Fan Yinzhong, Shi Baobao*, Liu Jikai*, Currephila A, a new chromanol derivative from the endophytic fungus Curreya pityophila. Records of Natural Products, 2024, 18, 285-289.
五、近年授权专利：
（2）石宝宝, 刘吉开, 艾洪莲, 冯涛, 李正辉。一种来源于日本蛇根草的新型异胡豆苷类衍生物及其制备方法和应用，ZL202210074390.1
（3）刘吉开, 石宝宝, 黄蓉, 王献, 陈乾, 董智慧, 沈慧慧, 伍兴。一种细叶萼距花精致组分和单体化合物的制备方法及其在化妆品中的应用, ZL202310428961.1
