肖新才 教授 湖北省新世纪高层次人才工程第三层次人选,主要从事新型给药系统研制和生物医用材料的研究。组建了民族药物的新型给药系统及其示踪评价研究团队。针对民族医药具有多成分、弱效应、协调整合作用特点,本团队研究内容包括多组分药物的化学成分分析、药效分析、给药系统设计(包括纳米给药,经皮给药,靶向给药)、剂型制备、工业化设备和工艺研究、以及临床前研究和临床研究等一系列研究。目的是为了让产于民族地区的和在民族地区广泛应用的天然药物的剂型升级和价值提升,因而对民族医药赋予时代感。
学习经历
1992.09---1996.07 在武汉化工学院就读并获化工过程机械工学学士学位
1996.09---1999.06 在武汉化工学院就读获化工过程机械工学硕士学位
2000.09---2003.06 在四川大学就读获化工过程机械工学博士研究生
工作经历
1999.07-2000.08 武汉化工学院从事教学和科研工作,讲师;
2003.09-2006.02: 武汉大学化学学院从事博士后工作;
2006.02- 威尼斯wns8885556生命科学学院、药学院从事教学和科研工作,副教授、教授
重要学术组织任职情况
国际期刊Journal of Applied Polymer Science评审专家,2006年8月起
湖北省创新基金项目评审专家,2006年5月起
承担的重要项目:
1.微重力下梯度型快速环境响应凝胶的构建、结构模拟及释药示踪,国家自然科学基金项目(21978329),2020.1—2023.12, 主持;
2. 分载两类药的耦合式环境响应型靶向给药系统的研究, 国家自然科学基金项目(21276287),2013.1—2016.12, 主持;
3.环境感应微泵元件的研制及其控释放传质特性, 国家自然科学基金项目(20976202),2010.1—2012.12, 主持;
4.环T型结构温度敏感凝胶微球研制及其给药特性研究,湖北省自然科学基金(2009CDB161),2010.1—2011.12, 主持。
代表作:
1. Liu Meng, Zhao Dan, Lv Hui, Liang Yun-Jing, Yang Yan-Nan, Hong Zong-Guo, Liu Jing-Xue, Dai Kang ⃰, Xiao Xin-Cai ⃰. Controllable fabrication and oil-water separation properties of polyethylene terephthaloyl- ethylenediamine-IPN-poly(N-Isopropylacrylamide) microcapsules, Polymers 2023, 15(1): 53.
2. Tan Hong-Fei, Zhao Dan, Liu Ming-Xing, Hong Zong-Guo, Liu Jing-Xue, Dai Kang ⃰, Xiao Xin-Cai ⃰. Docking design of the different microcapsules in aqueous solution and its quantitative on-off study, Polymers 2023, 15(5): 1131.
3. Xiong Xiao-Cui, Zhao Dan, Dai Kang, Xiao, Xin-Cai⃰. Coaxial ring-layered poly(N-isopropylacrylamide) gel columns of improved thermoresponses. Materials Chemistry and Physics 2019, 253(10): 123421.
4. Dan Zhao, Ma Wen-Ting, Xiao Xin-Cai ⃰. Recognition of sweat latent fingerprints with green-emitting carbon dots. Nanomaterials 2018, 8, 612(1-10) .
5. Zhang Rui-Lian, Guan Ya-Lan, Xiao Mi, Xiao Xin-Cai ⃰. Mobile gates driven by intermolecular hydrogen bonding. ChemistrySelect 2017, 2, 279 –282.
6. Du Huan-Huan,Xiao Xin-Cai ⃰.Fabrication of rapidly-responsive switches based on the coupling effect of polyacrylamide and poly(acrylic acid) without IPN structures.RSC Advances 2015,5:88021-88026.
7. Li Ying, Xiao Xin-Cai ⃰. Laterally sandwich-typed hydrogel columns with liner poly(N- isopropylacrylamide) layer: Preparation, swelling/deswelling kineticsanddrug delivery characteristics. Journal of Wuhan University of Technology-Materials Science Edition 2012, 27: 115-119.
8. Lu Cheng, Xiao Xin-Cai ⃰. Poly(N-isopropylacrylamide)-based vertically sandwich-typed hydrogel with fast temperature-response speed and its controlled- release characteristics. Journal of Wuhan University of Technology- Materials Science Edition 2012, 27: 280-284.
9. Xiao Xin-Cai⃰. A novel structure having linear poly(N-isopropylacrylamide) chains with rapid response to temperature changes. Advanced Materials Research 2012, 396-398: 205-208.
10. Wang Zhen-Huan, Xiao Xin-Cai ⃰. Preparation of core-shell microspheres by changing reaction solvent. Advanced Materials Research 2013, 634-638:2242-2245.
11. Xiao Xin-Cai,Hong Zong-Guo⃰. Firstborn microcrystallization method to prepare nanocapsules containing artesunate. International Journal of Nanomedicine 2010, 5: 483–486.
12. Xiao Xin-Cai ⃰. Effect of the initiator on thermosensitive rate of poly(N-isopropylacrylamide) hydrogels. eXPRESS Polymer Letter 2007,1: 232–235.
13. Xiao Xin-Cai ⃰. Surface-ionized thermosensitive poly(N-isopropylacrylamide) hydrogels with faster response. e-Polymers 2007, 091
14. Xiao Xin-Cai, Zhuo Ren-Xi ⃰, Xu Jian, Chen Li-Gui. Effects of reaction temperature and reaction time on positive thermosensitivity of microspheres with poly(acrylamide)/ poly(acrylic acid) IPN shells. European Polymer Journal 2006, 42: 473-478.
15. Xiao Xin-Cai, Chu Liang-Yin, Chen Wen-Mei, Wang Shu, Xie Rui. Preparation of submicron-sized monodispersed thermoresponsive core-shell hydrogel microspheres. Langmuir 2004, 20: 5247-5253.
16. Xiao Xin-Cai, Chu Liang-Yin, Chen Wen-Mei, Wang Shu, Li Yan. Positively thermo-sensitive monodisperse core-shell microspheres. Advanced Functional Materials 2003, 13: 847-852.