出生年月:1990-01
民 族:汉
职 称:副教授
学科专业:真菌天然产物化学与合成生物学
邮 箱:xinyangli@scuec.edu.cn
教育经历
2015.09-2019.06:浙江大学,医学博士
2012.09-2015.06:南京中医药大学,医学硕士
2008.09-2012.06:陕西中医药大学,医学学士
工作经历
2023.07至今:威尼斯wns8885556药学院,副教授
2019.09-2022.03,东京大学,博士后,合作导师:Ikuro Abe教授
主要研究方向
1. 真菌天然产物生物合成途径解析
2. 真菌天然产物生物合成酶学机制研究
3. 基于基因组挖掘手段的天然产物发现及其生物合成研究
科研项目
国家自然科学基金青年基金项目(22307148),2024.01-2026.12,主持
代表性研究成果
1. Xinyang Li, Jinzhong Xu*, Pinmei Wang, Wanjing Ding. Novel Indole Diketopiperazine Stereoisomers from a Marine-Derived Fungus Aspergillus sp. Mycology. 2023, 14, 1-10.
2. Xinyang Li†, He-Ping Chen†, Lin Zhou†, Jing Fan, Takayoshi Awakawa, Takahiro Mori, Richiro Ushimaru*, Ikuro Abe*, Ji-Kai Liu*. Cordycicadins A-D, Antifeedant Polyketides from the Entomopathogenic Fungus Cordyceps cicadae JXCH1. Org. Lett. 2022, 24, 8627-8632.
3. Qing-Yuan Wang†, He-Ping Chen†, Kai-Yue Wu, Xinyang Li*, Ji-Kai Liu*. Antibacterial and β-Site amyloid precursor protein cleaving enzyme 1 inhibitory polyketides from the fungus Aspergillus chevalieri. Front. Microbiol. 2022, 13, 1051281.
4. Lin Zhou†, He-Ping Chen†, Xinyang Li*, Ji-Kai Liu*. Ganoaustralins A and B, Unusual Aromatic Triterpenes from the Mushroom Ganoderma australe. Pharmaceuticals. 2022, 15, 1520.
5. Xinyang Li†, Takayoshi Awakawa†, Takahiro Mori, Meiqi Ling, Bin Wu, Ikuro Abe*. Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J. Am. Chem. Soc. 2021, 143, 21425-21432.
6. Xinyang Li, Jian-ming Lv, Dan Hu, Ikuro Abe*. Biosynthesis of Alkyne-containing Natural Products. RSC Chem. Biol. 2021, 2, 166-180.
7. Suoyu Cen, Jia Jia, Yichao Ge, Yihan Ma, Xinyang Li, Jihua Wei, Yuefan Bai, Xiaodan Wu, Jianfeng Song, Hongkai Bi, Bin Wu*. A New Antibacterial 3,5-dimethylorsellinic Acid-based Meroterpene from the Marine Fungus Aspergillus sp. CSYZ-1. Fitoterapia, 2021, 152, 104908.
8. Jinyan Jiang, Xinyang Li, Takahiro Mori, Takayoshi Awakawa*, Ikuro Abe*. Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis. Chem. Pharm. Bull., 2021, 69, 444-446.
9. Xinyang Li, Wanjing Ding, Pinmei Wang, Jinzhong Xu*. Two Novel Aspochalasins from the Gut Fungus Aspergillus sp. Z4. Mar. Drugs, 2018, 16, 343.
10. Xinyang Li, Zhanhai Zhao, Wanjing Ding, Bin Ye, Pinmei Wang, Jinzhong Xu*. Aspochalazine A, a Novel Polycyclic Aspochalasin from the Fungus Aspergillus sp. Z4. Tetrahedron Lett, 2017, 58, 2405-2408.
(†Co-first author; *Corresponding author)