基本信息
姓名：王文静
出生年月：1990年1月
民族：汉族
职称：讲师
学科方向：药物化学
研究方向：天然药物化学
邮箱：wangwj0122@163.com
教育及工作经历
2020.10—至今 威尼斯wns8885556药学院，讲师
2018.6—2020.5 华中科技大学基础医学院，博士后（合作导师：张勇慧教授、王小川教授）
2015.9—2018.9 华中科技大学药学院，医学博士（导师：张勇慧教授）
2012.9—2015.6 沈阳药科大学，理学硕士
2008.9—2012.6 湖北中医药大学，理学学士
教学工作
累计承担多门本科生和研究生课程教学工作，主要包括《结构生物学》、《药学仪器分析》、《高等中药化学》、《中药化学前沿》等；发表核心教研论文1篇，参编学术专著1部。指导国家级“大学生创新训练计划”1项，并获“优秀项目奖”；指导研究生团队获“建行杯”省级铜奖1项，“互联网+”校级奖2项
主要荣誉和获奖
2024年，威尼斯wns8885556“优秀班导师”
2022年，威尼斯wns8885556“第六届科普讲解大赛”三等奖
并多次获评威尼斯wns8885556“创新指导优秀教师”、“挑战杯”大学生课外学术科技作品竞赛“优秀指导老师”
科研项目
1. 内生真菌Aspergillus aculeatus中新颖结构抗耐药细菌活性色原酮二聚体的定向挖掘及其作用机制解析，国家自然科学基金面上项目，2024.1-2027.12，49万元。
2. 石蒜内生菌简青霉次生代谢产物及其生物活性研究，国家自然科学基金青年项目，2020.01-2022.12，24万元。
3. 简青霉次生代谢产物及其生物活性研究，中国博士后科学基金面上项目，2019.1-2020.12，8万元。
4. 分子网络驱动的Penicillium属真菌中新型抗三阴乳腺癌活性分子定向挖掘及其作用机制研究，武汉市自然科学基金探索计划（晨光计划），2024.6-2026.6，10万元。
5. 细果角茴香内生真菌Aspergillus versicolor化学成分及其生物活性研究，威尼斯wns8885556中央高校基本科研业务费项目，2022.3-2024.3，5万元。
代表性研究成果
截至目前，已在Organic Letters、Journal of Natural Products、Phytochemistry等本领域权威期刊上发表SCI论文30余篇
(1) Shuzhi Liu#, Wenjing Wang#, Qingpei Liu, Ming Yao, Liangxiu Liao, Shuaibiao Gao, Yi Yu; Xiaolong Yang(*), Emerindanols A and B: Two bipolyhydroindenol sesterterpenes with 5/6–6/5 coupled ring system discovered by genome mining, Organic Letters, 2024, 26, 4475.
(2) Wenjing Wang, Junguo Huang, Liangxiu Liao, Xiaolong Yang, Chunmei Chen, Junjun Liu, Hucheng Zhu(*), Yonghui Zhang(*), Chae-type cytochalasans from coculture of Aspergillus flavipes and Chaetomium globosum, Phytochemistry, 2024, 219, 113961.
(3) Sulu Qin, Jiaxin Ding, Chengyun Huang, Jing Li, Ming Yao, Qingpei Liu, Wenjing Wang(*), Xiaolong Yang(*), Secondary metabolites from Pseudallescheria boydii and their anti-melanoma activity, Tetrahedron, 2023, 147, 133663.
(4) Liangxiu Liao, Junguo Huang, Qingpei Liu, Ming Yao, Wenjing Wang(*), Xiaolong Yang(*), Two new quinazoline alkaloids produced by Aspergillus versicolor and their antimicrobial activities, Journal of Asian Natural Products Research, 2023, 26, 320.
(5) Wenjing Wang#, Liangxiu Liao#, Zediao Huang, Futing Wei, and Xiaolong Yang(*), Thiazolo[5,4‑b]pyridine alkaloid and seven ar-bisabol sesquiterpenes produced by the endophytic fungus Penicillium janthinellum, ACS Omega, 2022, 7, 35280–35287.
(6) Liangxiu Liao, Zediao Huang, Futing Wei, Wenjing Wang(*), Xiaolong Yang(*), New chromone analog and pyrrole alkaloid produced by Penicillium sclerotiorum and their antibacterial activity, Journal of Asian Natural Products Research, 2022, 25, 225.
(7) Qinglin Mou, Shengxiang Yang, Ting Xiang, Wenwen Liu, Jian Yang, Lanpin Guo(*), Wenjing Wang(*), Xiaolong Yang(*), New cytochalasan alkaloids and cyclobutane dimer from an endophytic fungus Cytospora chrysosperma in Hippophae rhamnoides and their antimicrobial activities, Tetrahedron Letters, 2021, 87, 153207.
(8) Wenjing Wang, Chong Dai, Jianping Wang, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae, Current Medical Science, 2020, 40, 232–238.
(9) Wenjing Wang, Fanrong Zeng, Qiong Bie, Chong Dai,Chunmei Chen, Qingyi Tong, Junjun Liu, Jianping Wang, Yuan Zhou, Hucheng Zhu(*), Yonghui Zhang(*), Cytochathiazines A−C: Three Merocytochalasans with a 2H-1,4-Thiazine Functionality from Coculture of Chaetomium globosum and Aspergillus flavipes, Organic Letters, 2018, 20, 6817-6821.
(10) Wenjing Wang, Jiaojiao Gong, Xiaorui Liu, Chong Dai, Yanyan Wang, Xiaonian Li, Jianping Wang, Zengwei Luo, Yuan Zhou, Yongbo Xue, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Cytochalasans produced by the co-culture of Aspergillus flavipes and Chaetomium globosum, Journal of Natural Products, 2018, 81, 1578–1587.
(11) Wenjing Wang, Xiao Wan, Junjun Liu, Jianping Wang, Hucheng Zhu, Chunmei Chen(*), Yonghui Zhang(*), Two New Terpenoids from Talaromyces purpurogenus, Marine Drugs, 2018,16, 150.
(12) Wenjing Wang, Danyi Li, Yanchun Li, Huiming Hua, Enlong Ma(*), Zhanlin Li(*). Caryophyllene Sesquiterpenes from the Marine-Derived Fungus Ascotricha sp. ZJ-M‑5 by the One Strain-Many Compounds Strategy. Journal of Natural Products, 2014, 77, 1367–1371.
