出生年月:1973年3月
民族:汉族
职称:教授
学科专业:有机化学
研究方向:有机合成化学和金属有机化学
电话:15087127510
电子邮箱:2015084@mail.scuec.edu.cn
简历:教育背景和科研经历:
1994.9-1998.7 兰州大学化学化工学院,学士
1998.9-2001.7 兰州大学化学化工学院,硕士,导师:涂永强院士
2001.9-2004.7 中科院上海有机化学研究所, 博士,导师:麻生明院士
2004.8-2005.11美国内布拉斯加州立大学林肯分校,博士后,导师:David B.Berkowitz 教授
2005.12-2010.8美国俄亥俄州立大学,博士后,导师:T.V. RajanBabu 教授
2010.8-2015.6 中国科学院昆明植物研究所,研究员,博士生导师
2015.6-至今威尼斯wns8885556药学院,教授,博士生导师
代表性研究成果
1.Yanli Xie, Dongdong Xu, Wen-Wu Sun, Shi-Jin Zhang, Xiao-Ping Dong, Bin Liu,* Yingbi Zhou,* Bin Wu*. Cobalt Catalyzed Oxidative Dimerization of 2-Phenylpyridine Derivatives . Asian J. Org. Chem. 2016, 5, 961.
2.Qun-Ying Yu, Hong-Ming Zhong, Wen-Wu Sun, Shi-Jin Zhang, Pei Cao,* Xiao-Ping Dong, Hong-Bo Qin, Ji-Kai Liu, Bin Wu*. Palladium-Catalyzed C(sp3)-H Functionalization at the C(3) Position of L-Pipecolinic Acid Derivatives. Asian J. Org. Chem. 2016, 5, 608.
3.Shi-Jin Zhang, Wen-Wu Sun, Pei Cao,* Xiao-Ping Dong,* Ji-Kai Liu, Bin Wu*. Stereoselective Synthesis of Diazabicyclic b-Lactams through Intramolecular Amination of Unactivated C(sp3)-H Bonds of Carboxamides by Palladium Catalysis. J. Org. Chem. 2016, 81, 956.
4.Pei Cao, Zhen-Jie Li, Wen-Wu Sun, Shashwat Malhotra, Yuan-Liang Ma, Bin Wu*, Virinder S. Parmar*. Cascade N-Alkylation/Hemiacetalization for FacileConstruction of the Spiroketal Skeleton of AcortatarinAlkaloids with Therapeutic Potentiality in DiabeticNephropathy. Natural Products and Bioprospecting. 2015, 5, 37.
5.Wen-Wu Sun, Pei Cao, Ren-Qiang Mei, Yue Li, Yuan-Liang Ma, Bin Wu*. Palladium-Catalyzed Unactivated C(sp3)-H Bond Activation and Intramolecular Amination of Carboxamides: A New Approach to β-lactams. Org. Lett. 2014, 16, 480.
6.Bin Wu, Judith C. Gallucc, Jon R. Parquette*, and T. V. RajanBabu*. Bimetallic catalysis in the highly enantioselective ring–opening reactions of aziridines. Chem. Sci., 2014, 5, 1102.
7.Bin Wu, Jon R. Parquette*, and T. V. RajanBabu*. Regiodivergent Ring Opening of Chiral Aziridines. Science. 2009, 326, 1662.
(This paper was highlighted by Chemistry World News and the website address iswww.rsc.org/chemistryworld/News/2009/December/17120903.asp.
This paper was highlighted by Chemical & Engineering News and the website address iswww.pubs.acs.org/cen/news/87/i51/8751notw4.html.)
8.Bin Wu, Judith C. Gallucci, Jon R. Parquette*, and T. V. RajanBabu*. Enantioselective Desymmetrization of meso-Aziridines with TMSN3 or TMSCN Catalyzed by Discrete Yttrium Complexes. Angew. Chem. Int. Ed. 2009, 48, 1126. (highlighted by inside cover and review paper: Angew. Chem. Int. Ed. 2009, 48, 2082.)
9.Nicola J. Baxter, Matthew W. Bowler, Tooba Alizadeh, Matthew J. Cliff, Andrea M. Hounslow, Bin Wu, David B. Berkowitz, Nicholas H. Williams, Steven J. Gamblin, G. Michael Blackburn,* and Jonathan P. Waltho.* Atomic details of near-transition state conformersfor enzyme phosphoryl transfer revealedby MgF3− rather than by phosphoranes.Proc. Natl. Acad. Sci.U.S.A. 2010, 107, 4555.
10.David B. Berkowitz*, Bin Wu, and Huijie Li. A Formal [3,3]-sigmatropic Rearrangement Route to Quaternary a-Vinyl Amino Acids: Use of Allylic N-PMP Trifluoroacetimidates. Org.Lett. 2006, 8, 971.
11.Shengming Ma*, Bin Wu, Xuefeng Jiang, and Shimin Zhao. Studies on Pd (II)-Catalyzed Synthesis of (Z)-a-Haloalkylidene-b-lactones from Cyclocarbonylation of 2-Alkynols and the Subsequent Coupling Reactions. J. Org. Chem. 2005, 70, 2568.
12.Shengming Ma*, Bin Wu, and Xuefeng Jiang. PdCl2-Catalyzed Efficient Transformation of Propargylic Amines to (E)-a-Chloroalkylidene-b-lactams. J. Org. Chem. 2005, 70, 2588.
13.Shengming Ma*, Bin Wu, and Zhangjie Shi. An Efficient Synthesis of 4-Halo-5-hydroxyfuran-2(5H)-ones via the Sequential Halolactonization and g-Hydroxylation of 4-Aryl-2,3-alkadienoic Acids. J. Org. Chem. 2004, 69, 1429.
14.Shengming Ma*, Bin Wu, and Shimin Zhao. A Mild and Efficient Synthesis of (Z)-a-Chloroalkylidene-b-lactones via the PdCl2-Catalyzed Cyclocarbonylation of 2-Alkynols. Org.Lett. 2003, 5, 4429.
15.Yan Xing Jia, Bin Wu, Xin Li, Shi Kuo Ren, Yong Qiang Tu,* Albert S. C. Chen, and William Kitching. Synthetic Studies of the HIV-1 Protease Inhibitive Didemnaketals: Stereocontrolled Synthetic Approach to the Key Mother Spiroketals. Org.Lett. 2001, 3, 847.
16.Xin Li, Bin Wu, Xue Zhi Zhao, Yan Xing Jia, Yong Qiang Tu,* De Run Li. An Interesting AlEt3-Promoted Stereoselective Tandem Rearrangement / Reduction of a-Hydroxy (or Amino) Heterocyclopane. Synlett., 2003, 623.
17.Yan Xing Jia, Xin Li, Bin Wu, Xue Zhi Zhao, and Yong Qiang Tu.* A convergent synthesis of the spiroketal moiety of the HIV-1 protease inhibitors didemnaketals. Tetrahedron, 2002, 58, 1697.
授权专利
1.吴滨、孙文武、曹沛、赵金华、杨莲。N-喹啉基取代的-内酰胺类化合物,其合成方法和以该类化合物为活性成分的药物组合物及其应用,专利号:ZL 201310428596.0
2. 吴滨、孙文武。顺式稠环的-内酰胺化合物的合成方法,专利号:ZL 201310549472.8
获奖:
2011 入选“云南省高端科技人才引进计划”