杨金明

发布时间:2019-04-25 浏览次数:

https://mtgl.scuec.edu.cn/_vsl/4D6EB2AF943B77F7EB956707B91A0CEF/538E83DF/69A5E

个人简介

职称:教授

民族:汉族

学科专业:有机化学、药物化学

研究方向:1)药物化学导向的有机合成方法学研究;

2)过渡金属催化合成反应;

3)不对称合成。

办公室:药学院13-428

电子邮箱:jmyang@scuec.edu.cn; yangjm1225@163.com

热忱欢迎有机化学、药物化学及相关专业优秀学生报考本课题组研究生,同时欢迎优秀的本科生加入课题组交流学习。


学习经历

2010.09-2015.06:华东理工大学,有机化学,理学博士(硕博连读),导师:施敏 教授/研究员

2011.08-2015.06:中国科学院上海有机化学研究所,联合培养博士,导师:施敏 教授/研究员

2006.09-2010.06:湖北大学,应用化学,理学学士


工作经历

2024.03-至今:威尼斯wns8885556,药学院(教授、硕士生导师)

2018.11-2024.03:威尼斯wns8885556,药学院(副教授、硕士生导师)

2016.06-2018.06:西班牙加泰罗尼亚化学研究所,欧盟玛丽居里学者计划 (博士后项目),导师:Antonio M. Echavarren 教授

2015.07-2016.05:上海药明康德新药开发有限公司,管理培训生


承担项目与课题

1)国家自然科学基金青年项目(No. 221013032022-2024 主持

2)湖北省自然科学基金面上项目(No. 2023AFB6642023-2025 主持

3)中央高校基本科研业务费专项资金重点项目(No.CZZ240062024-2026 主持

4)威尼斯wns8885556引进人才科研启动基金重点项目(No. YZZ180092019-2023 主持,已结题

5)科技部外国文教专家项目(No. G2022185002L2022.1-2023.12 主持,已结题

6)湖北省自然科学基金青年项目(No. 2020CFB2502020-2022 主持,已结题

7)科技部外国文教专家项目(No. G202000171172020.1-2020.12 主持,已结题

8)中央高校基本科研业务费专项资金项目(No.CZQ190142019-2020 主持,已结题

9)欧洲研究理事会(ERC玛丽居里学者计划No.7025242016-2018 主持,已结题


主要获奖及荣誉

2021-2022学年优秀班导师

2018年入选湖北省高层次人才计划

2016年入选欧盟“玛丽居里”学者计划

2014年获得博士研究生国家奖学金


学术兼职

中国化学会/美国化学会会员,受邀担任国际学术期刊Organic LettersChemical CommunicationsThe Journal of Organic ChemistryBioconjugate ChemistryCurrent Topics in Medicinal ChemistryCurrent Organic Chemistry审稿人。


论文成果

(1) Ze Zhou, Xiang Huang, Qing-Yi Wei, Yi-Lin Wang, Bin Wu, Jin-Ming Yang.*. Access to Piperazine-Fused Pyrrolocarbazoles Enabled by Acid-Catalyzed Stereoselective Hydroarylation of Ynamide-Indoles and Subsequent Diels-Alder Reactions/Aromatizations. Organic Letters, 2024, 26, 7273–7278. (SCI一区top期刊,Nature指数收录)

(2) Jin-Ming Yang,* Guang-Chao Feng, Xiang Huang, Yi-Lin Wang, Qing-Yi Wei, Bin Wu.* Rhodium(III)-Catalyzed Intramolecular Cyclization and Sequential Aromatization of Ynamides with Propargyl Esters: Access to 2,5-Dihydropyrroles and Pyrroles. Organic Letters, 2024, 26, 6191-6196. (SCI一区top期刊,Nature指数收录)

(3) Xin-Yu Yang,§ Jin-Ming Yang,§* Bin Wu.* TMSOTf-Promoted Cyclization of Indole-2-methyl-a-aminoketones: Access to 4-Aryl-Substituted b-Carbolines. Organic Letters, 2024, 26, 1105-1109. (§共同一作,SCI一区top期刊,Nature指数收录)

(4) Guang-Chao Feng, Jun-Chi Li, Xiang Huang, Ji-Kai Liu, Bin Wu, Jin-Ming Yang.* Cascade Hydroarylation/Diels-Alder Cycloaddition of Alkynylindoles with Electron-Deficient Alkynes and Alkenes. Chemical Communications, 2024, 60, 328-331. (†共同一作,SCI二区top期刊,Nature指数收录)

(5) Qing-Yi Wei, Ze Zhou, Meng-Lian Yao, Ji-Kai Liu, Bin Wu, Jin-Ming Yang.* Rhodium(III)-Catalyzed Intermolecular [3+3] Annulation of Benzoxazines with Quinone Compounds: Access to Spiro-Heterocyclic Scaffolds. Chemical Communications, 2023, 59, 11520-11523. (†共同一作,SCI二区top期刊,Nature指数收录)

(6) Meng-Lian Yao, Xiao-Yuan Wang, Guang-Chao Feng, Ji-Kai Liu, Bin Wu,* Jin-Ming Yang.* Palladium(II)-Catalyzed Intramolecular [2 + 2 + 2] Annulation of Indolyl 1,3-Diynes: Construction of Azepino-Fused Carbazoles. Organic Letters, 2023, 25, 4615-4620. (SCI一区top期刊,Nature指数收录)

(7) Jin-Ming Yang,* Meng-Lian Yao, Jun-Chi Li, Ji-Kai Liu, Bin Wu.* Access to Azepino-annulated Benzo[c]carbazoles Enabled by Gold-Catalyzed Hydroarylation of Alkynylindoles and Subsequent Oxidative Cyclization. Organic Letters, 2022, 24, 6505-6509. (SCI一区top期刊,Nature指数收录)

(8) Zhe Fan,^ Shao-Fei Ni,^ Jin-Yu Pang, Li-Ting Guo, Hao Yang, Ke Li, Cheng Ma, Ji-Kai Liu,* Bin Wu,* Jin-Ming Yang.* Cu(I)-catalyzed cross-coupling rearrangements of terminal alkynes with tropylium tetrafluoroborate: Facile access to barbaralyl substituted allenyl acid esters and 7-alkynyl cycloheptatrienes. The Journal of Organic Chemistry, 2022, 87, 3066-3078. (SCI二区top期刊)

(9) Inmaculada Martín-Torres, Gala Ogalla, Jin-Ming Yang, Antonia Rinaldi, Antonio M. Echavarren*. Enantioselective alkoxycyclization of 1,6-enynes with gold(I)-cavitands: Total synthesis of Mafaicheenamine C. Angewandte Chemie International Edition, 2021, 60, 9339-9344. (SCI一区top期刊,Nature指数收录,入选Top Downloaded ArticleIF2021: 15.336)

(10) Jin-Ming Yang, Cheng-Zhi Zhu, Xiang-Ying Tang,* Min Shi*. Rhodium(II)-catalyzed intramolecular annulation of 1-sulfonyl-1,2,3-triazoles with pyrrole and indole rings: facile synthesis of N-bridgehead azepine skeletons. Angewandte Chemie International Edition, 2014, 53, 5142-5146. (SCI一区top期刊,Nature指数收录,入选ESI高引用论文,已引用163IF2014: 11.261)

(11) Jin-Ming Yang, Peng-Hua Li, Yin Wei, Xiang-Ying Tang,* Min Shi*. Gold(I)-catalyzed highly stereoselective synthesis of polycyclic indolines: construction of four contiguous stereocenters. Chemical Communications, 2016, 52, 346-349. (SCI一区top期刊, Nature指数收录)

(12) Jin-Ming Yang, Xiang-Ying Tang,* Min Shi*. Gold(I)-catalyzed intramolecular cycloisomerization of propargylic esters with furan rings. Chemistry – A European Journal, 2015, 21, 4534-4540. (SCI二区top期刊)

(13) Jin-Ming Yang, Xiang-Ying Tang, Yin Wei,* Min Shi*. Phosphine-promoted cyclization of dicyclopropenones. Advanced Synthesis & Catalysis, 2013, 355, 3545-3552. (SCI二区top期刊)

(14) Jin-Ming Yang, Zhen Zhang, Yin Wei,* Min Shi*. Silver(I)-catalyzed tandem reactions of N-activated aziridine-propargylic esters to pyrrolidin-3-one derivatives. Tetrahedron Letters, 2012, 53, 6173-6176. (SCI三区)

(15) Jin-Ming Yang, Rui Zhang, Wen-Feng Wang, Zhen Zhang, Min Shi*. Axially chiral N-heterocyclic carbene gold(I) complex catalyzed asymmetric Friedel-Crafts/cyclization reaction of nitrogen-tethered 1,6-enynes with indole derivatives. Tetrahedron Asymmetry 2011, 22, 2029-2038. (SCI三区)

(16) Wen-Feng Wang, Jin-Ming Yang, Fei-Jun Wang, Min Shi*. Axially chiral N-heterocyclic carbene gold(I) complex catalyzed asymmetric cycloisomerization of 1,6-enynes. Organometallics 2011, 30, 3859-3869. (SCI二区)

(17) Peng-Hua Li, Jin-Ming Yang, Yin Wei,* Min Shi*. Silver(I)-catalyzed intramolecular cyclizations of epoxide-propargylic esters to 1,4-oxazine derivatives. ChemistryOpen 2017, 6, 21-24. (SCI三区)


专利

(1) 杨金明,姚梦莲,吴滨,一种稠环吲哚类化合物及其制备方法和应用,授权日期:2024.02.27,授权专利号:ZL202210679227.8,发明专利,中国。

(2) 杨金明,李俊驰,一种稠环氢化异喹啉化合物及其制备方法和应用,申请号或专利号:202310955290.4,申请日期:2023.7.31,发明专利,中国。

(3) 杨金明,李俊驰,吴滨,封广超,黄翔,一种稠环奥苷菊环类化合物及其制备方法,申请号或专利号:202310955283.4,申请日期:2023.7.31,发明专利,中国。


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