一、教育和工作简历：

1.2020/1-至今，威尼斯wns8885556，药学院，教授，博士生导师

2.2019/7-2020/6，德国莱布尼兹汉诺威大学，访问学者

3.2015/7-2019/12，威尼斯wns8885556，药学院，副教授，硕士生导师

4.2010/7-2015/6，中国科学院昆明植物研究所，植物化学与西部植物资源持续利用国家重点实验室，副研究员

5.2005/9–2010/6，中国科学院昆明植物研究所，硕博连读，药物化学，博士

6.2000/9–2004/7，西南大学，学士

二、研究方向：

1.药用植物化学成分的结构与功能

2.真菌天然产物的结构与功能。主要研究特色为真菌特有天然产物的结构、功能及其生物合成。

三、主要荣誉、获奖和社会兼职：

国家民委中青年英才培养计划；中国科学院卢嘉锡青年人才奖；威尼斯wns8885556第七届三育人标兵；中国科学院院长优秀奖；中国科学院青年创新促进会会员；分获云南省自然科学奖励一、二等奖；Journal of Fungi、Natural Products and Bioprospecting和Food & Medicine Homology期刊编委；中国菌物学会菌物化学专业委员会副主任；湖北省药学会药化专委会委员

四、学术研究：

从事药用植物、真菌天然产物及其功能研究。聚焦真菌特有天然产物的结构及其功能，尤其是真菌特有聚酮和萜类分子，发现具有独特结构的抗炎活性分子“口蘑三萜”，发现具有显著镇痛活性的真菌特有二萜等。获得新的天然产物700余个，多个分子被评为研究热点。主持国家自然科学基金、省部级项目等科研基金13项，在Org Lett，Org Chem Front,J Org Chem，J Nat Prod，J Agri Food Chem等多种学术期刊以第一作者或通讯作者发表研究论文130余篇。

（一）主要科研基金：

1.国家自然科学基金面上项目（2022）：真菌特有guanacastane型二萜结构及其镇痛作用研究（22277147），主持。

2.国家自然科学基金面上项目（2018）：“口蘑三萜”的挖掘及其抗炎作用研究（81872762），主持。

3.国家自然科学基金项目（2011）：四种有毒高等真菌毒性成分挖掘及毒性评价（81102346），主持。

4.中央高校基本科研业务费专项资金重点培育项目：口蘑属三萜分子抗炎先导化合物的发现，主持。

（二）发表的主要研究论文：

1.Juan He, Jiao-Xian Du, Qian-Ru Zhao, Ya-Pei Liu, Yan-Long Yang,* Ji-Kai Liu,*Tao Feng*. Biochemical and genetic basis of guanacastane diterpene biosynthesis in basidiomycete fungi.Organic Letters2023, 25, 5345-5349.

2.Jing Li, Wen-Xuan Wang, Zheng-Hui Li, Juan He, Rong Huang, Yong-Sheng Zheng, Lan-Qing Li, Xian Wang,Tao Feng*, Ji-Kai Liu*. Xylaridines C and D, unusual thiopyranodipyridine alkaloids from the fungusXylaria longipes.Organic Letters2019, 21, 6145−6148.

3.Jing Li, Wen-Xuan Wang, He-Ping Chen, Zheng-Hui Li, Juan He, Yong-Sheng Zheng, Huan Sun, Rong Huang, Qing-Xia Yuan, Xian Wang,Tao Feng*, Ji-Kai Liu*. (±)-Xylaridines A and B, highly conjugated alkaloids from the fungus Xylaria longipes.Organic Letters2019, 21, 1511-1514.

4.Wen-Xuan Wang, Xin-Xiang Lei, Hong-Lian Ai, Xue Bai, Jing Li, Juan He, Zheng-Hui Li, Yong-Sheng Zheng,Tao Feng*, Ji-Kai Liu*.Cytochalasans from the endophytic fungusXylaria cf. curtawith resistance reversal activity against fluconazole-resistantCandida albicans.Organic Letters2019, 21, 1108−1111.

5.Wen-Xuan Wang, Xin-Xiang Lei, Yan-Ling Yang, Zheng-Hui Li, Hong-Lian Ai, Jing Li,*Tao Feng,* Ji-Kai Liu,* Xylarichalasin A, a halogenated hexacyclic cytochalasan from the fungusXylaria cf. curta.Organic Letters2019, 21, 6957-6960.

6.Tao Feng, Kai-Ting Duan, Shi-Jun He, Bin Wu, Yong-Sheng Zheng, Hong-Lian Ai, Zheng-Hui Li, Juan He, Jian-Ping Zuo*, Ji-Kai Liu*.Ophiorrhines A and B, two immunosuppressive monoterpenoid indole alkaloids fromOphiorrhiza japonica.Organic Letters2018, 20, 7926–7928

7.Wei Li, Juan He,Tao Feng*, Hui-Xiang Yang, Hong-Lian Ai, Zheng-Hui Li, Ji-Kai Liu*.Antroalbocin A, an antibacterial sesquiterpenoid from higher fungusAntrodiella albocinnamomea,Organic Letters2018, 20, 8019–8021

8.Hui-Xiang Yang, Hong-Lian Ai,Tao Feng*, Wen-Xuan Wang, Bin Wu, Yong-Sheng Zheng, Huan Sun, Juan He, Zheng-Hui Li, Ji-Kai Liu*.Trichothecrotocins A–C, antiphytopathogenic agents from potato endophytic fungusTrichothecium crotocinigenum.Organic Letters2018, 20, 8069–8072

9.Tao Feng,Xue-Mei Li,Jun He,Hong-Lian Ai,He-Ping Chen,Xiao-Nian Li, Zheng-Hui Li, and Ji-Kai Liu,Nicotabin A, a sesquiterpenoid derivative fromNicotiana tabacum.Organic Letters2017,19, 5201−5203.

10.Tao Feng, Yan Li, Ya-Ping Liu, Xiang-Hai Cai, Yuan-Yuan Wang,and Xiao-Dong Luo,Melotenine A, a cytotoxic monoterpenoid indole alkaloid fromMelodinus tenuicaudatus,Organic Letters2010, 12(5),968-971.

11.Tao Feng, Xiang-Hai Cai, Yan Li, Yuan-Yuan Wang, Ya-Ping Liu, Ming-Jin Xie,and Xiao-Dong Luo,Melohenines A and B, two unprecedented alkaloids fromMelodinus henryi,Organic Letters2009, 11(21),4834-4837.

12.Jin-Tao Ma, Xin-Yue Dong, Zheng-Hui Li, He Yan, Juan He,* Ji-Kai Liu,*Tao Feng*. Antibacterial metabolites from kiwi endophytic fungusFusarium tricinctum, a potential biocontrol strain for kiwi canker disease.Journal of Agricultural and Food Chemistry2023, 71, 7679-7688.

13.Hong-Lian Ai, Bao-Bao Shi, Wei Li, Juan He, Zheng-Hui Li,Tao Feng*, Ji-Kai Liu*. Bipolarithizole A, an antifungal phenylthiazole-sativene merosesquiterpenoid from the potato endophytic fungusBipolaris eleusines.Organic Chemistry Frontiers2022, 9, 1814-1918.

14.Ying Huang, Shuai-Bing Zhang, He-Ping Chen, Zhen-Zhu Zhao, Zhong-Yu Zhou, Zheng-Hui Li,Tao Feng*, Ji-Kai Liu*.New acetylenic acids and derivatives from the edible mushroomCraterellus lutescens(Cantharellaceae).Journal of Agricultural and Food Chemistry2017, 65, 3835−3841.

15.He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Ying Huang, Shuai-Bing Zhang, Yang Tang, Jian-Neng Yao, Lin Chen, Masahiko Isaka,Tao Feng^*, Ji-Kai Liu^*,Anti-proliferative and anti-inflammatory lanostane triterpenoids from the Polish edible mushroomMacrolepiota procera.Journal of Agricultural and Food Chemistry2018, 66, 3146-3154.

16.Tao Feng,Jin-Long Cai,Xue-Mei Li,Zhong-Yu Zhou,Zheng-Hui Li,and Ji-Kai Liu,Chemical constituents and their bioactivities of mushroomPhellinus rhabarbarinus.Journal of Agricultural and Food Chemistry2016, 64, 1945−1949.

17.Tao Feng, Jia Su, Zhi-Hui Ding, Yong-Tang Zheng, Yan Li, Ying Leng, and Ji-Kai Liu, Chemical constituents and their bioactivities of “Tongling White Ginger” (Zingiber officinale),Journal of Agricultural and Food Chemistry2011, 59, 11690-11695.

18.Shuai-bing Zhang, Ying Huang, Shi-jun He, He-ping Chen, Bin Wu, Shan-yong Li, Zhen-zhu Zhao, Zheng-hui Li, Xian Wang, Jian-ping Zuo,Tao Feng*, Ji-Kai Liu*.Heterocyclic compounds from the mushroomAlbatrellus confluensand their inhibitions against lipopolysaccharides-induced B lymphocyte cell proliferation.Journal of Organic Chemistry2018, 83, 10158−10165.（二区top）

19.Zhen-Zhu Zhao, He-Ping Chen,Bin Wu,Ling Zhang,Zheng-Hui Li,Tao Feng*, Ji-Kai Liu*.Matsutakone and matsutoic acid, two (nor)steroids with unusual skeletons from the edible mushroomTricholoma matsutake.Journal of Organic Chemistry2017, 82, 7974−7979.（二区top）

20.Ming-Xuan Gao, Feng Wu, Si-Qiong Teng, He-Ping Chen, Zheng-Hui Li, Juan He,*Tao Feng,* Ji-Kai Liu*. Triquinane sesquiterpene glycosides from the basidiomyceteAntrodiella zonata.Journal of Natural Products2023, 86, 1736-1745.

21.Bao-bao Shi, Hong-Lian Ai, Kai-Ting Duan,Tao Feng*, Ji-Kai Liu*. Ophiorrhines F and G, key biogenetic intermediates of ophiorrhine alkaloids fromOphiorrhiza japonicaand their immunosuppressant activities.Journal of Natural Products2022, 85, 453-457.

22.Juan He, Rui Ma, Zheng-Hui Li,Tao Feng*, Ji-Kai Liu*. Taccachatrones A−G, highly oxidized steroids from the rhizomes ofTacca chantrieriiand their cytotoxicity assessment.Journal of Natural Products2021, 84, 2265−2271.

23.Meng Wang, Jiao-Xian Du, Yang Hui-Xiang, Quan Dai, Ya-Pei Liu, Juan He, Yi Wang, Zheng-Hui Li,Tao Feng,*Ji-Kai Liu*.Sesquiterpenoids from cultures of the basidiomycetesIrpex lacteus.Journal of Natural Products2020, 83, 1524-1531.

24.Ya-Pei Liu, Quan Dai, Wen-Xuan Wang, Juan He, Zheng-Hui Li,Tao Feng,* Ji-Kai Liu, Psathyrins: antibacterial diterpenoids fromPsathyrella candolleana.Journal of Natural Products2020, 83, 1725-1729.

25.Tao Feng,Xiao-Qing Gan,Yun-Li Zhao,Shuai-Bing Zhang,He-Ping Chen,Juan He,Yong-Sheng Zheng,Huan Sun,Rong Huang,Zheng-Hui Li*,Ji-Kai Liu*.Tricholopardins A and B, anti-inflammatory terpenoids from the fruiting bodies ofTricholoma pardinum.Journal of Natural Products2019, 82, 45−50.

26.Tao Feng, Xiang-Hai Cai,Ya-Ping Liu,Yan Li,Yuan-Yuan Wang, Xiao-Dong Luo,Melodinines A–G, monoterpenoid indole alkaloids fromMelodinus henryi,Journal ofNaturalProducts2010, 73, 22-26.

27.Tao Feng, Yan Li, Yuan-Yuan Wang, Xiang-Hai Cai, Ya-Ping Liu, Xiao-Dong Luo, Cytotoxic indole alkaloids fromMelodinus tenuicaudatus,Journal ofNaturalProducts2010, 73, 1075-1079.

28.Tao Feng, Yan Li, Xiang-Hai Cai, Xun Gong, Ya-Ping Liu, Rong-Ting Zhang, Xiang-Yun Zhang, Qin-Gang Tan and Xiao-Dong Luo, Monoterpenoid indole alkaloids fromAlstonia yunnanensis,Journal ofNaturalProducts2009,72,1836-1841.

29.Fa-Lei Zhang,Tao Feng*. Diterpenes specially produced by fungi: Structures, biological activities and biosynthesis (2010–2020).Journal of Fungi2022, 8, 244.

30.Quan Dai, Fa‐Lei Zhang,Tao Feng*. Sesquiterpenoids specially produced by fungi: structures, biological activities, chemical and biosynthesis (2015–2020).Journal of Fungi2021, 7, 1026.

（三）近年授权专利：

1.冯涛、刘吉开、李正辉，口蘑菌素甲及其制备方法与应用、口蘑菌素乙及其制备方法与应用, ZL201810010131.6

2.冯涛、刘吉开、何隽、李正辉、石晨，口蘑三萜化合物、其制备方法、提取物及其应用, ZL202010980531.7

3.冯涛、刘吉开、杨会祥，一种二萜类衍生物及其制备方法与镇痛药物、小脆柄菇发酵得物及其乙酸乙酯萃取液，ZL202210290942.2