Personal Profile
Nationality: China
Date of Birth: May, 1981
E-mail: tfeng@mail.scuec.edu.cn
Phone (Fax): +86-(0)27 67841275
Mobil: +86-(0)15827269869
Professional Career
2015.07-current Associate professor. Master supervisor. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, China
2013.01-2015.06 Associate professor. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany (KIB), Chinese Academy of Sciences (CAS), Kunming, China
2010.07-2012.12 Research Assistant. State Key Laboratory of Phytochemistry and Plant Resources in West China, KIB, CAS, Kunming, China
Education
2005.09-2010.06 M.Sc. and Ph.D. in Medicinal Chemistry. State Key Laboratory of Phytochemistry and Plant Resources in West China, KIB, CAS, Kunming, China
2000.09-2004.07 B. Sc. in Sericultural Science. Southwest University, Chongqing, China
Research Experience
2005-2010：Achieved PhD. Investigations on the isolation, structural elucidation, and bioactivities of natural products from plants. Highlight in studies on the monoterpenoid indole alkaloids (MIA) from plants of the family Apocynaceae. More than 200 MIAs were obtained, including new skeletons, as well as the significant anti-tumor cell lines activities.
2011-current：Carry out the isolation, structural elucidation, and bioactivities of natural products from higher fungi. Focus on the leading compounds for drug discovery. Carry out studies on mushroom toxins. Highlight on the discovery of novel Tricholoma terpenoids with significant anti-inflammatory activities. Carry out secondary metabolites from endophytic fungi, searching for anti-pathogenic agents.
Research Project
Two projects supported by the National Natural Science Foundation of China (NSFC), total: 790,000.00 (RMB)
Other eight research projects, total: 1,410,000.00 (RMB)
Publications and Patents
More than 70 articles have been published as the first or corresponding author. Won the first prize of Yunnan Province Natural Science Award.
List of Selected Publications
(1) Jing Li, Wen-Xuan Wang,* Zheng-Hui Li, Juan He, Rong Huang, Yong-Sheng Zheng, Lan-Qing Li, Xian Wang, Tao Feng,* Ji-Kai Liu,* Xylaridines C and D, unusual thiopyranodipyridine alkaloids from the fungus Xylaria longipes. Organic Letters 2019, 21, 6145−6148.
(2) Jing Li, Wen-Xuan Wang, He-Ping Chen, Zheng-Hui Li, Juan He, Yong-Sheng Zheng, Huan Sun, Rong Huang, Qing-Xia Yuan, Xian Wang, Tao Feng,* Ji-Kai Liu,* (±)-Xylaridines A and B, highly conjugated alkaloids from the fungus Xylaria longipes. Organic Letters 2019, 21, 1511-1514.
(3) Wen-Xuan Wang, Xin-Xiang Lei, Hong-Lian Ai,* Xue Bai, Jing Li, Juan He, Zheng-Hui Li, Yong-Sheng Zheng, Tao Feng,* Ji-Kai Liu,* Cytochalasans from the endophytic fungus Xylaria cf. curta with resistance reversal activity against fluconazole-resistant Candida albicans. Org. Lett. 2019, 21, 1108−1111.
(4) Tao Feng, Xiao-Qing Gan, Yun-Li Zhao, Shuai-Bing Zhang, He-Ping Chen, Juan He, Yong-Sheng Zheng, Huan Sun, Rong Huang, Zheng-Hui Li, and Ji-Kai Liu, Tricholopardins A and B, anti-inflammatory terpenoids from the fruiting bodies of Tricholoma pardinum. J. Nat. Prod. 2019, 82, 45−50.
(5) Juan He, Man-Si Yang, Wen-Xiang Wang, Zheng-Hui Li, Waill Ahmed Mohamed Elkhateeb, Ting-Chi Wen, Hong-Lian Ai* and Tao Feng,* Anti-phytopathogenic sesquiterpenoid-xanthoneadducts from potato endophytic fungus Bipolaris eleusines. RSC Advances 2019, 9, 128–131.
(6) Tao Feng, Kai-Ting Duan, Shi-Jun He, Bin Wu, Yong-Sheng Zheng, Hong-Lian Ai, Zheng-Hui Li, Juan He, Jian-Ping Zuo, and Ji-Kai Liu, Ophiorrhines A and B, two immunosuppressive monoterpenoid indole alkaloids from Ophiorrhiza japonica. Organic Letters, 2018, 20, 7926–7928
(7) Wei Li, Juan He, Tao Feng*, Hui-Xiang Yang, Hong-Lian Ai, Zheng-Hui Li, and Ji-Kai Liu, Antroalbocin A, an antibacterial sesquiterpenoid from higher fungus Antrodiella albocinnamomea, Organic Letters, 2018, 20(24), 8019–8021
(8) Hui-Xiang Yang, Hong-Lian Ai, Tao Feng*, Wen-Xuan Wang, Bin Wu, Yong-Sheng Zheng, Huan Sun, Juan He, Zheng-Hui Li, and Ji-Kai Liu, Trichothecrotocins A–C, antiphytopathogenic agents from potato endophytic fungus Trichothecium crotocinigenum. Organic Letters, 2018, 20, 8069–8072
(9) Shuai-bing Zhang, Ying Huang, Shi-jun He, He-ping Chen, Bin Wu, Shan-yong Li, Zhen-zhu Zhao, Zheng-hui Li, Xian Wang, Jian-ping Zuo, Tao Feng*, Ji-Kai Liu*, Heterocyclic compounds from the mushroom Albatrellus confluens and their inhibitions against lipopolysaccharides-induced B lymphocyte cell proliferation. Journal of Organic Chemistry 2018, 83, 10158−10165.
(10) Shuai-Bing Zhang, Ying Huang, He-Ping Chen, Zheng-Hui Li, Bin Wu, Tao Feng*, Ji-Kai Liu*, Confluenines A–F, N-oxidized L-isoleucine derivatives from the edible mushroom Albatrellus confluens, Tetrahedron Letters 2018, 59, 3262–3266.
(11) Shuai-Bing Zhang, Ying Huang, Shi-Jun He, He-Ping Chen, Zheng-Hui Li, Bin Wu, Jian-Ping Zuo,* Tao Feng,* and Jikai Liu,* Albatredines A and B, a pair of epimers with unusualnatural heterocyclic skeletons from edible mushroom Albatrellus confluens, RSC Advances 2018, 8, 23914–23918.
(12) Shuai-Bing Zhang, Zheng-Hui Li, Marc Stadler, He-Ping Chen, Ying Huang, Xiao-Qing Gan, Tao Feng*, Ji-Kai Liu*, Lanostane triterpenoids from Tricholoma pardinum with NO production inhibitory and cytotoxic activities. Phytochemistry 2018, 152, 105-112.
(13) He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Ying Huang, Shuai-Bing Zhang, Yang Tang, Jian-Neng Yao, Lin Chen, Masahiko Isaka, Tao Feng*, Ji-Kai Liu*, Anti-proliferative and anti-inflammatory lanostane triterpenoids from the Polish edible mushroom Macrolepiota procera. Journal of Agricultural and Food Chemistry 2018, 66, 3146-3154.
(14) Tao Feng, Xue-Mei Li, Jun He, Hong-Lian Ai, He-Ping Chen, Xiao-Nian Li, Zheng-Hui Li, and Ji-Kai Liu, Nicotabin A, a sesquiterpenoid derivative from Nicotiana tabacum. Organic Letters 2017, 19, 5201−5203.
(15) Zhen-Zhu Zhao, He-Ping Chen, Bin Wu, Ling Zhang, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*, Matsutakone and matsutoic acid, two (nor)steroids with unusual skeletons from the edible mushroom Tricholoma matsutake. Journal of Organic Chemistry 2017, 82(15), 7974−7979.
(16) Ying Huang, Shuai-Bing Zhang, He-Ping Chen, Zhen-Zhu Zhao, Zhong-Yu Zhou, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*, New acetylenic acids and derivatives from the edible mushroom Craterellus lutescens (Cantharellaceae). Journal of Agricultural and Food Chemistry 2017, 65, 3835−3841.
(17) Jian-Neng Yao, Lin Chen, Yang Tang, He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Tao Feng*, Ji-Kai Liu*, Lanostane triterpenoids from fruiting bodies of basidiomycete Stereum sp., structures and biological activities. Journal of Antibiotics 2017, 70(12): 1104-1111.
(18) Tao Feng, Jin-Long Cai, Xue-Mei Li, Zhong-Yu Zhou, Zheng-Hui Li, and Ji-Kai Liu, Chemical constituents and their bioactivities of mushroom Phellinus rhabarbarinus. Journal of Agricultural and Food Chemistry 2016, 64, 1945−1949.
(19) Tao Feng, Jin-Long Cai, Xue-Mei Li, Zhong-Yu Zhou, Rong Huang, Yong-Sheng Zheng, Zheng-Hui Li, Ji-Kai Liu, Phellibarin D with an unprecedented triterpenoid skeleton isolated from the mushroom Phellinus rhabarbarinus. Tetrahedron Letters 2016, 57(31): 3544–3546
(20) He-Ping Chen, Zhen-Zhu Zhao, Zheng-Hui Li, Ze-Jun Dong, Kun Wei, Xue Bai, Ling Zhang, Chun-Nan Wen, Tao Feng*, Ji-Kai Liu*, Novel natural oximes and oxime esters with a vibralactone backbone from the basidiomycete Boreostereum vibrans, ChemistryOPEN 2016, 5, 142-149.
(21) Tao Feng, Xiao-Ning Li, Bao-Hong Zhang, Yan Li, Xiang-Hai Cai, Ya-Ping Liu, Xiao-Dong Luo, Gardovatine, a novel Strychnos–Strychnos bisindole alkaloid with cytotoxicity from Gardneria ovata, Bioorganic & Medicinal Chemistry Letters 2013, 23(21), 5563–5565.
(22) Tao Feng, Jia Su, Zhi-Hui Ding, Yong-Tang Zheng, Yan Li, Ying Leng, and Ji-Kai Liu, Chemical constituents and their bioactivities of “Tongling White Ginger” (Zingiber officinale), Journal of Agricultural and Food Chemistry 2011, 59(21), 11690-11695.
(23) Tao Feng, Yan Li, Ya-Ping Liu, Xiang-Hai Cai, Yuan-Yuan Wang, and Xiao-Dong Luo, Melotenine A, a cytotoxic monoterpenoid indole alkaloid from Melodinus tenuicaudatus, Organic Letters 2010, 12(5), 968-971.
(24) Tao Feng, Xiang-Hai Cai, Ya-Ping Liu, Yan Li, Yuan-Yuan Wang, Xiao-Dong Luo, Melodinines A–G, monoterpenoid indole alkaloids from Melodinus henryi, Journal of Natural Products 2010, 73, 22-26.
(25) Tao Feng, Yan Li, Yuan-Yuan Wang, Xiang-Hai Cai, Ya-Ping Liu, Xiao-Dong Luo, Cytotoxic indole alkaloids from Melodinus tenuicaudatus, Journal of Natural Products 2010, 73, 1075-1079.
(26) Tao Feng, Xiang-Hai Cai, Yan Li, Yuan-Yuan Wang, Ya-Ping Liu, Ming-Jin Xie, and Xiao-Dong Luo, Melohenines A and B, two unprecedented alkaloids from Melodinus henryi, Organic Letters 2009, 11(21), 4834-4837.
(27) Tao Feng, Yan Li, Xiang-Hai Cai, Xun Gong, Ya-Ping Liu, Rong-Ting Zhang, Xiang-Yun Zhang, Qin-Gang Tan and Xiao-Dong Luo, Monoterpenoid indole alkaloids from Alstonia yunnanensis, Journal of Natural Products 2009, 72, 1836-1841.
