CURRICUM VITAE
Name: Yang Guangzhong Sex: Male Date of Birth: Nov. 27, 1968
Educational background: Ph.D. Title: Professor
ADDRESS: School of Pharmaceutical Sciences, South-Central Minzu University; No 182, Minyuan Road, Hongshan District; Wuhan, Hubei, China, 430074
E-mail: yanggz888@126.com
1 EDUCATION:
B.A. 1986.9-1990.6 Department of chemistry, South-Central Minzu University
M. S. 1990.7-1993.6 Institute of Organic synthesis, Central China Normal
University
Ph. D. 1998.9-2001.7 Shanghai Institute of Materia Medica, Chinese Academy of Sciences (SIMM, CAS)
2 WORK EXPERIENCE
1993.7-1998.8 Institute of Organic synthesis, Central China Normal University, Lecturer
2001.12-2003.12 Forestry and Forest Products Research Institute, Japan, JSPS
Postdoctoral Fellowship
2004.1-at present School of Pharmaceutical Sciences, South-Central Minzu University, Professor
3 RESEARCH FIELD
My research interests focus on the discovery of novel natural products derived from ethnomedicines, as well as the structural modifications and biological activities of natural products. My research group has conducted studies on the chemical constituents and biological activities of over 30 ethnomedicinal plants, resulting in the isolation and identification of more than 1,500 compounds. These compounds include terpenoids, alkaloids, flavonoids, phenylpropanoids, and saponins, with over 400 new compounds identified from these plants. Prof. Yang has led and participated in the completion of more than 10 research projects, including those funded by the National Major New Drugs Innovation and Development program, the National Key Research and Development, the National Natural Science Foundation, National Key Laboratories, and various provincial and ministerial projects. Additionally, Prof. Yang has received two provincial and ministerial science and technology awards, published over 150 academic papers—more than 70 of which are indexed in the Science Citation Index, and obtained eight Chinese invention patents, along with one clinical approval for an innovative traditional Chinese medicine drug.
4 PUBLICATIONS
(1) Xueni Li, Qingqing Li, Jing Xu, Shuang Yang, Xin Hu, Zhengyang Lu, Gui Mei,
Yu Chen, Zhinan Mei, Guangzhong Yang, Isolation and antihyperglycemic effects of garcibractinols A–H, intricate polycyclic polyprenylated acylphloroglucinols from the fruits of Garcinia bracteata, Bioorganic Chemistry, 2023,138, 106651.
(2) Wenli Xie, Hefeng Nian, Xueni Li, Jing Xu, Yu Chen, Zhinan Mei, Guangzhong Yang, Prenylated sulfonyl amides from the leaves of Glycosmis pentaphylla and their potential anti-proliferative and anti-inflammatory activities, Arabian Journal of Chemistry, 2023, 16, 104528.
(3) Xue Tan, Xiaoyang Han, Haida Teng, Qingqing Li, Yu Chen, Xinxiang Lei, Guangzhong Yang, Structural Elucidation of Garcipaucinones A and B From Garcinia paucinervis Using Quantum Chemical Calculations, Journal of Natural Products, 2021, 84, 972−978.
(4) Jinhong Xu, Hui Xiong, Zhongqiu Zhao, Miao Luo, Yankun Ju, Guangzhong Yang, Zhinan Mei, Genistein suppresses allergic contact dermatitis through regulating the MAP2K2/ERK pathway, Food &Function, 2021, 12, 4556–4569.
(5) Xian-Ju Huang, Jing Wang, Azhar Muhammad, Hai-Ying Tong, Da-Gui Wang, Jun Li, Awais Ihsan, Guang-Zhong Yang, Systems pharmacology-based dissection of mechanisms of Tibetan medicinal compound Ruteng as an effective treatment for collagen-induced arthritis rats, Journal of Ethnopharmacology, 2021, 272, 113953.
5 Scientific research projects
(1) Hubei Provincial Major Science and Technology Special Project (2021ACB003), 2021-2024.
(2) National Major New Drugs Innovation and Development (2017ZX09301060006)，2017-2021.
(3) National Key Technology Research and Development Program (2012BAI27B06)，2012-2014.
(4) State Key Laboratory of Drug Research (SIMM0901KF-02), 2009-2010.
(5) National Natural Science Foundation (30670215), 2007-2009.
