Minzu Road, Wuhan, 430074, R.P. China
their action mechanism study ;
Apr. 2015~Mach. 2017
School of Medicine, Yale University
From Sep. 2001 to Jun. 2011
College of Pharmacy, Chengdu University of Traditional Chinese Medicine
●Chemical constituent separation and
●Biosassay combination chemical method for quality control and evaluation for TCM;
●Comparative Medicine of International Traditional Medicine.A.
|
Governmental
|
2017
|
Principle Investigator(PI),Key methods for quality control and new drug development of Ethnic medicine, National Major Scientific and Technological Special Project for “Significant New Drugs Development” (No. 2017ZX09301060-001), 2017-2020, amount ￥1,223,000
|
2017
|
Principle Investigator(PI), “Investigation on the effectiveness substance identification and quality control of Chinese Herbal Medicine based on efficacy tropism and spectrum-effect relationship grey correlation analysis ”, National Natural Science Foundation of China (N0. 81773893) , 2018-2021, amount ￥550,000
|
2015
|
Principle Investigator(PI),Herbal drugimprovement by active ingredients knock in and knock out, take Sodium aescinate as an example,Hubei Nature Science Foundation (N0. 2015CFB302) , 2015-2016, amount ￥30,000
|
2015
|
Principle Investigator(PI),“Investigation on the molecular mechanism”, Young Talents of Science and Technology in Wuhan Morning Program, 2015-2016, ￥100,000
|
2012
|
Principle Investigator(PI), ”Investigation of the processing effecting on Chinese herbal medicine ascending and descending tropism by multi-modality biological imaging”, National Natural Science Foundation of China (N0. 81202935) , 2012-2015, amount ￥230,000
[1] Liang Shuai(1), Deng Xin (1), Lei Lei, Zheng Yao, Ai Jiao, Linlin Chen, Zhinan Mei, Yung-Chi Cheng(*) and Yongshen Ren(*). The comparative study of the therapeutic Effects and mechanisms of Baicalin, fBaicalein and their Combinations on ulcerative colitis rat Fronters in Pharmacology Ethnopharmacology. 2019, https://doi.org/10.3389/fphar.2019.01466 【SCI二区，IF=3.831】
[2] Ren Yongshen(*,1), Lei Lei(1), Deng Xin, Zheng Yao, Li Yan, Li Jun, Mei Zhinan (*). Novel application of neural network modelling for multicomponent herbal medicine optimization. Sci Rep.https://doi.org/10.1038/s41598-019-51956-6【SCI三区，IF=4.011】
[3] Feifei Zhang(1), Jie Ba (1) , Lei Lei, Yao Zheng, Xin Deng, Weijun Li, Peng Liu, Yongshen Ren(*). Investigation on the Optimum Preparation of Peach Gum Polysaccharides and Its Therapeutic Effects and Mechanisms on Acute Pyelonephritis in Vivo and Vitro. Evidence-based Complementary and Alternative Medicine. 2109,https://doi.org/10.1155/2019/2729343【SCI三区，IF=1.984】
[4] Yongshen Ren(1,*) , Yao Zheng(1), Lei Lei, Xin Deng, Xinqiao Liu, Xukun Deng (*). Dandelion polyphenols protect against acetaminophen induced hepatotoxicity in mice via activating the Nrf-2/HO-1 and inhibiting the JNK signaling pathway. Chin J Nat Med. 2020.1 【SCI三区，IF=1.773】
[5] Yongshen Ren, Ziliang Yuan, Kangle Lv, Jie Sun, Zehui Zhang(*) , Quan Chi. Selective and metal-free oxidation of biomass derived 5-hydroxymethylfurfural to 2,5-diformylfuran over nitrogen-doped carbon materials. Green Chemistry. 2018. 20: 4946【SCI一区，IF=8.586】
[6] Yongshen Ren, Yanxin Wang, Xun Li, Zehui Zhang(*), Quan Chi. Selective hydrogenation of quinolines into 1,2,3,4-tetrahydroquinolines over a nitrogen doped carbon-supported Pd catalyst. New J. Chem. 2018. 42, 16694-16702【SCI三区，IF=3.201】
[7] Jie Yang, Shihao Deng, Mi Huang, Xinhua Ma, Ping Song, Jingwen Du, Yun Huang, Yanzhang Wen, Yongshen Ren(*), Xinzhou Yang(*). Inhibitory effect of kurarinone on growth of human non-small cell lung cancer: an experimental study both in vitro and in vivo studies. Fronters in Pharmacology Ethnopharmacology. 2018. DOI: 10.3389/fphar.2018.00252 【 SCI二区，IF=3.831】
[8] Wing Lam, Ren Yongshen, Fulan Guan, Zaoli Jiang, William Cheng, Shwuhuey Liu, Yung-Chi Cheng(*). Mechanism Based Quality Control (MBQC) for quality control of herbal products: a case study YIV-906 (PHY906). Fronters in Pharmacology Ethnopharmacology. 2018. doi: 10.3389/fphar.2018.01324【 SCI二区，IF=3.831】
[9] Yongshen Ren, Bing Liu, Zehui Zhang, Jintao Lin, Silver-exchanged heteropolyacid catalyst (Ag1H2PW): An efficient heterogeneous catalyst for the synthesis of 5-ethoxymethylfurfural from 5-hydroxymethylfurfural and fructose，Journal of Industrial and Engineering Chemistry. 2015, 21: 1127-1131【 SCI二区，IF=4.421】
[10] Yongshen Ren(*, 1), Jiao Ai (1), Xinqiao Liu, Shuai Liang, Yao Zheng, Xin Deng, Yan Li, Jing Wang, Linlin Chen, Zhinan Mei(*) . Anticoagulant active ingredients identification of total saponin extraction of different Panax medicinal plants based on grey relational analysis combined with UPLC-MS and molecular docking. J Ethnopharm. 【 SCI二区，IF=3.414】
[11] Liang shuai, Zheng Yao, Lei Lei, Deng Xin, Ren Yongshen(*).The protective effect of Corydalis on Alzheimer's disease by the inhibitions of NF-κB/MAPK pathway. J Ethnopharmacol. 2020 (In review) 【SCI二区，IF=3.414 】
[12] Yao Zheng (1), Lei Lei (1), Shuai Liang, Jiao Ai , Yongshen Ren (*) .Comparative study on the protective effect of fresh/dry dandelion extracts on APAP-overdose caused acute liver Injury . Planta Medica. 2020 (In review) 【SCI二区，IF=2.746 】
[13] Manrong Tan (1)，Yongshen Ren (1)，Yan Dan(*)，Mengxiang Hong，Longhu Chen，Lingling Qiu，Yan Yan，Jianyu Li，Xiaohe Xiao(*)，Detection of microorganisms in different growth states basedon microcalorimetry，J Therm Anal Calorim，2012, 109: 1069-1075【 SCI三区，IF=1.953】
[14] Yongshen Ren，Ping Zhang，Dan Yan，Yan Yan，Longhu Chen，Lingling Qiu，Zhinan Mei，Xiaohe Xiao，Application ofmicrocalorimetryof Escherichia coli growth and discriminant analysis to th equality assessment of a Chinese herbal injection(Yinzhihuang). Acta Pharmaceutica Sinica B，2012,2(2): 278-285【SCI一区，IF=6.014】
[15] Yongshen Ren (1)，Ping Zhang (1)，Yan Dan (*) ，JB Wang，Xiaoxi Du，XiaoHe Xiao (*). A strategy for the detection of quality fluctuation of a Chinese herbal injection based on chemical fingerprinting combined with biological fingerprinting.，J Pharm Biomed Anal., 2011, 56(2): 436-442 【 SCI三区，IF=2.831】
