Name: Guangwen Shu
Discipline: Chinese Medicine
Research direction:
Active substances and mechanism of traditional drugs in the treatment of liver diseases
Email: shuguangwen@whu.edu.cn
Experience:
2002/09-2006/06, School of life sciences, Wuhan University, Bachelor.
2006/09-2011/06, Institute of Biochemistry and cell biology, Shanghai Institute of life sciences, Chinese Academy of Sciences, Doctor.
Since 2011/07, School of Pharmaceutical Sciences, Central-South University for Nationalities, Faculty.
Selected publications:
1. Chlorogenic acid methyl ester exerts strong anti-inflammatory effects via inhibiting the COX-2/NLRP3/NF-κB pathway. Food Funct. 2018 Dec 13; 9(12): 6155-6164.
2. Activity of Isoliensinine in Improving the Symptoms of Type 2 Diabetic Mice via Activation of AMP-Activated Kinase and Regulation of PPARγ. J Agric Food Chem. 2017 Aug 23; 65(33): 7168-7178.
3. Amplexicaule A exerts anti-tumor effects by inducing apoptosis in human breast cancer. Oncotarget. 2016 Apr 5; 7(14): 18521-30.
4. Antidiabetic effects of flavonoids from Sophora flavescens EtOAc extract in type 2 diabetic KK-ay mice. J Ethnopharmacol. 2015 Aug 2; 171: 161-70.
5. Chemical composition of total flavonoids from Polygonum amplexicaule and their pro-apoptotic effect on hepatocellular carcinoma cells: Potential roles of suppressing STAT3 signaling. Food Chem Toxicol. 2015 Jun; 80: 62-71.
