He-Bin Tang Professor
Email: hbtang2006@mail.scuec.edu.cn
Team Website: http:/s/53/t/1559/94/d7/info103639.htm
Tel: 86-27-67842332
uCurriculum Vitae
•HunanCollege of Traditional Chinese Medicine, B.M., 1996
•Zhuzhou Traumatological Hospital of Traditional Chinese Medicine, Hunan, ENT doctor, 1996-1998
•HiroshimaUniversity, Hiroshima, Japan, M.S., 2002
•HiroshimaUniversity, Hiroshima, Japan, Ph.D., 2005
•HiroshimaUniversity, Hiroshima, Japan, Assistant Professor, 2005-2009
•South-CentralUniversity for Nationalities, Professor, since 2009
uResearch Interests
•Pharmacological research on early warning and precise medication of gradual progression from fatty liver disease to liver cancer.
•Pharmacological research on anti-liver cancer activity of Traditional Chinese Medicine.
•Mechanism of chronic pain
uAssociation and Awards
•Clinical research branch of China information association for tradtional Chinese medicine and pharmacy, Standing Director;
•Chinese medicine experimental pharmacology branch of China association for Chinese medicine, Director
•The Hubei Pharmacological Society, Director;
uRepresentative Publications (*Corresponding author)
1.2. Chen MT, Yang YJ, Li YS, Li XJ, Zhang WK, Wang JP, Wang X, Tian GH, Tang HB*. Shengfu oil enhances the healing of full-thickness scalded skin accompanying the differential regulation of β-Catenin, Dlk1, and COX-2. Frontiers in Pharmacology. 2017, 8: 801. doi: 10.3389/fphar.2017.00801.
2.Ning D, Zhang WK, Tian H, Li XJ, Liu M, Li YS*, Tang HB. The involvement of β-Catenin/COX-2/VEGF axis in NMDA-caused retinopathy. Journal of Ophthalmology. 2017; 2017: 9760501. doi: 10.1155/2017/9760501.
3.Li XJ, Mu YM, Qin QF, Zeng ZX, Li YS, Zhang WK, Tang HB*, Tian GH, Shang HC. Chronic high-dosage fish oil exacerbates gut-liver axis injury in alcoholic steatohepatitis in mice: The roles of endotoxin and IL-4 in Kupffer cell polarization imbalance. Toxicology Research. 2017, 6, 611-620.DOI: 10.1039/C7TX00037E
4.Zhang WK, Gu HW, Li XJ, Li YS, Tang HB*, Tian GH, Shang HC.The dark side of the force - lipid nanoparticles enhance the oncogenesis of diethylnitrosamine and result in liver cancer in mice. Nanomedicine: Nanotechnology, Biology, and Medicine. 2017, 13(2): 701-711. doi: 10.1016/j.nano.2016.09.017.
5.Zhang WK, Tao SS, Li TT, Li YS, Li XJ, Tang HB*, Cong RH, Ma FL, Wan CJ. Nutmeg oil alleviates chronic inflammatory pain through inhibition of COX-2 expression and substance P release in vivo. Food & Nutrition Research. 2016, 60: 30849.
6.Tian GH, Tao SS, Chen MT, Li YS, Li YP, Shang HC, Tang XY, Chen JX, Tang HB*. Electroacupuncture treatment alleviates central poststroke pain by inhibiting brain neuronal apoptosis and aberrant astrocyte activation. Neural Plasticity. 2016, 2016: 1437148.
7.Li YS, Leng CL, Chen MT, Zhang WK, Li XJ, Tang HB*, Shang HC, Zhu LH. Mouse hepatic neoplasm formation induced by trace level and low frequency exposure to diethylnitrosamine through β-catenin signaling pathway. Toxicology Research. 2016, 5:210-223.
8.Li XJ, Yang YJ, Li TT, Li YS, Zhang WK, Tang HB*. α-Pinene, linalool, and 1-octanol contribute to the topical anti-inflammatory and analgesic activities of frankincense by inhibiting COX-2. Journal of Ethnopharmacology. 2016, 179:22-26.
9.Li XJ, Mu YM, Li TT, Yang YL, Zhang MT, Li YS, Zhang WK, Tang HB*, Shang HC. Gynura procumbens reverses acute and chronic ethanol-induced liver steatosis through MAPK/SREBP-1c-dependent and -independent pathways. Journal of Agricultural and Food Chemistry. 2015, 63(38):8460-8471.
10.Li YS, Xi Y, Li XJ, Leng CL, Jia MM, Zhang WK, Tang HB*. Up-regulation of the biosynthesis and release of substance P through Wnt/β-catenin signaling pathway in rat dorsal root ganglion cells. PLoS One. 2015, 10(6): e0129701.
11.Li YS, Chen BF, Li XJ, Zhang WK, Tang HB*. Cytotoxicity of polyaniline nanomaterial on rat celiac macrophages in vitro. PLoS One. 2014, 9(9):e107361
12.Li XJ, Jia MM, Li YS*, Yang YL, Mao XQ, Tang HB. Involvement of substance p/neurokinin-1 receptor in the analgesic and anticancer activities of minimally toxic fraction from the traditional Chinese medicine Liu-Shen-Wan in vitro. Biological and Pharmaceutical Bulletin. 2014, 37(3):431-438.
13.Li L, Guo QL, Li J, Yan W, Leng CL, Tang HB*, Lu QW, Tang BE. Design of a polymer ligand for the one-step preparation of highly stable fluorescent Ag5 clusters for tissue labeling. Journal of Materials Chemistry B. 2013, 1, 3999-4004.
14.Li YS, Wang JX, Jia MM, Liu M, Li XJ, Tang HB*. Dragon's blood inhibits chronic inflammatory and neuropathic pain responses by blocking the synthesis and release of substance P in rats. Journal of Pharmacological Sciences. 2012,118: 43-54.
15.Li YS, Liu M, Nakata Y, Tang HB*. β-Catenin accumulation in nuclei of hepatocellular carcinoma cells up-regulates glutathione-s-transferase M3 mRNA.World Journal of Gastroenterology, 2011, 17:1772.
uRepresentative Grants
•Grant from National Natural Science Foundation of China: Protective mechanisms of Gynura procumbens against liver cancer through the inhibition of inflammatory feedback loop of“β-catenin/COX-2, No. 81673711, 2016;
•Grant from National Natural Science Foundation of China: A Study on Dai medicine Pabengban alleviating alcoholic live disease by activating AMPK in the gut-liver axies, No. 81403188, 2014;
•Grant from National Natural Science Foundation of China: Modulation mechanism of Shengfu Oil on scarless healing in full-thickness burn wounds, No. 81373842, 2013;
•Grant from National Natural Science Foundation of China: The regulatory role of Wnt/β-catenin signaling pathway in the development of primary hepatocellular carcinoma, No. 81101538, 2011;
•Grant from National Natural Science Foundation of China: The role of non-neuronal cells in the regulation of substance P release from dorsal root ganglion neurons, No. 81070887, 2010;
•Grant-in-Aid for Scientific Research (B) from the Japan Society for the Promotion of Science: Molecular mechanism of peptide neurotransmitter release from primary afferent neurons, No. 19790189, 2007.
